Publications

In review or an archive:

2023

81) F. Späth, A. S. Maier, M. Stasi, A. M. Bergmann, K. Halama, M. Wenisch, B. Rieger, J. Boekhoven
The Role of Chemically Innocent Polyanions in Active, Chemically Fueled Complex Coacervate Droplets
Angew. Chemie Int. Ed. (pdf)

80) A.M. Bergmann,* J. Bauermann,* G. Bertolucci,* C. Donau,* M. Stasi, A. Holtmannspötter, J. Jülicher, C. Weber, J. Boekhoven
Liquid spherical shells are a non-equilibrium steady state of active droplets
Nature Commun. (pdf)

79) X. Chen, H. Soria-Carrera, O. Zozulia, J. Boekhoven,
Suppressing catalyst poisoning in the carbodiimide-fueled
reaction cycle,
Chem. Sci. (pdf)

78) X. Chen,* B. Kriebisch,* A. M. Bergmann, J. Boekhoven
Design rules for reciprocal coupling in chemically fueled assembly 
Chem. Sci. (pdf)

77) Synthetic pathway dictates supramolecular structure
B. Kriebisch, J. Boekhoven
Nature Synthesis (pdf)

76) A. Heidecker, M. Stasi, A. Spears, J. Boekhoven, A. Pöthig
Silver and Gold Pillarplex Pseudorotaxanes from α,ω-Dicarboxylic Acids
ChemPlusChem (pdf)

75) L. Tebcharani, N. Akter, J. Gibbs, J. Boekhoven
Hydrolyzable emulsions as a release platform for hydrophobic drugs and DNA
Chem. Commun. (pdf)

74) X. Chen,* M. Würbser,* J. Boekhoven
Chemically fueled supramolecular materials,
Acc. Mater. (pdf)

73) X. Chen, J. Rodon-Fores, M. Stasi, A. Bergmann, K. Dai, M. Tena-Solsona, J. Boekhoven
A carbodiimide-fueled reaction cycle that forms transient 5(4H)-Oxazolones
J. Am. Chem. Soc. (pdf)

72) C. Donau, J. Boekhoven
The chemistry of chemically fueled droplets
Trends Chem. (pdf)

71) B. Kriebisch, C. Kriebisch, A. Bergmann, C. Wanzke, M. Tena-Solsona, J. Boekhoven
Tuning the Kinetic Trapping in Chemically Fueled Self-Assembly
ChemSystemsChem (pdf) and Cover art (pdf)

2022

70) M. Stasi, A. Monferrer, L. Babl, S. Wunnava, C. Dirscherl, D. Braun, P. Schwille, H. Dietz, J. Boekhoven,
Regulating DNA-Hybridization Using a Chemically Fueled Reaction Cycle
J. Am. Chem. Soc. (pdf)

69) J. Rodon-Fores, M. Würbser, M Kretschmer, B. Rieß, A.M. Bergmann, O. Lieleg, J. Boekhoven
A chemically fueled supramolecular glue for self-healing gels
Chem. Sci. (pdf)

68) C. Donau, F. Späth, M. Stasi, A. Bergmann, J. Boekhoven
Phase transitions in chemically fueled, multiphase complex coacervate droplets
Angew. Chemie. (pdf)

67) A. Bergmann,  C. Donau, F. Späth, K. Jahnke, K. Göpfrich, J. Boekhoven, 
Evolution and Single Droplet Analysis of Fuel-Driven Compartments by Droplet-Based Microfluidics
Angew. Chemie (pdf)

66) F. Schnitter, B. Riess, J. Boekhoven,
Memory, switches, and logic gates through bistability in chemically fueled crystals
Nature Commun. (pdf)

65) P. Schwarz, M. Tena Solsona,  K.Dai, J. Boekhoven,
Carbodiimide-fueled catalytic reaction cycles to regulate supramolecular processes
Chem. Commun. (pdf)

64) A rotating bioreactor for the production of biofilms at the solid-air interface,
Biotechnol. Bioeng (pdf)

63) Y. Xue, M. Stasi, N. Fehn, U. Heiz, J. Boekhoven, A. Kartouzian
Tunable Induced Circular Dichroism in Gels
Chirality (pdf)

2021

62) K. Dai, M. Tena-Solsona, J. Rodon Fores, J. Boekhoven,
Morphological transitions in chemically fueled self-assembly
Nanoscale (pdf)

61) B.J., Niebuur, H. Hegels, M. Tena-Solsona, P. Schwarz, J. Boekhoven, C.Papadakis,
Droplet formation by chemically-fueled self-assembly: the role of precursor hydrophobicity
J. Phys. Chem. (pdf)

60) M. Ha , S. Nader , S. Pawsey , J. Struppe, M. Monette , S. S.  Mansy , J. Boekhoven, V. K. Michaelis, Racing Towards Fast and Effective ¹⁷O Isotopic Labeling and NMR Spectroscopy of N-formyl-MLF-OH and Associated Building Blocks
J. Phys. Chem. (pdf)

59) L. Tebcharani, C. Wanzke,  T. Lutz, J. Rodon-Fores; O. Lieleg, J. Boekhoven
Emulsions of hydrolyzable oils for the zero-order release of hydrophobic drugs
J. Controlled Release (pdf)

58) M. Kretschmer, B. Winkeljann, B. A. K. Kriebisch, J. Boekhoven, O. Lieleg, 
Viscoelastic behavior of chemically fueled
supramolecular hydrogels under load and influence
of reaction side products
Comms Mat. (pdf)

57) P. Schwarz, L. Tebcharani, J. Heger,  P. Müller-Buschbaum, J. Boekhoven
Chemically Fueled Materials with a Self-Immolative Mechanism: Transient Materials with a Fast On/Off Response
Chem. Sci (pdf)

56) C. Kriebisch, A. Bergmann, J. Boekhoven,
Fuel-Driven Dynamic Combinatorial Libraries
J. Am. Chem. Soc. (pdf)

54) F. Schnitter, A. M. Bergmann, B. Winkeljann, J. Rodon Fores, O. Lieleg, J. Boekhoven,
Synthesis and characterization of molecular assemblies driven by carbodiimide-based fuels,
Nature Protocols (pdf)

55) M. Würbser, P. Schwarz, J. Heckel, A. Bergmann, A. Walther, Job Boekhoven,
Chemically Fueled Block Copolymer Self-Assembly into Transient Nanoreactors,
ChemSystemsChem (pdf)

53) F. Späth, C. Donau, A.M.  Bergmann, M. Kränzlein, C. Synatschke, B. Rieger, J. Boekhoven,
Molecular design rules for chemically fueled complex coacervate-based assemblies, 
J. Am. Chem. Soc. (pdf)

52) P. Schwarz, S. Laha, J. Janssen, T. Huss, J. Boekhoven, C. Weber,
Parasitic Behavior in Competing Chemically Fueled Reaction Cycles,
Chem. Sci (pdf)

51) F. Schnitter, J. Boekhoven
A Method to Quench Carbodiimide‐Fueled Self‐Assembly,  
ChemSystemsChem (pdf)

2020

50) B. Kriebisch, A. Jussupow, A. Bergmann, F. Kohler, H. Dietz, V. Kaila, J. Boekhoven,
Reciprocal coupling in chemically fueled assembly: a reaction cycle regulates self-assembly and vice versa,
J. Am. Chem. Soc. (pdf)

49) C. Donau, F. Späth, M. Sosson, B. Kriebisch, F. Schnitter, M. Tena-Solsona H. Kang, E. Salibi, M. Sattler, H. Mutschler, J. Boekhoven,
Active coacervate droplets as a model for membraneless organelles and protocells,
Nature Commun. (pdf)

48) M. Tena Solona, J. Janssen, C. Wanzke, F. Schnitter H. Park, B. Rieß, J. M. Gibbs, C. A. Weber, J. Boekhoven,
Accelerated Ripening in Chemically Fueled Emulsions,
ChemSystemsChem (pdf)

47) K. Dai, J. Rodon Fores, C. Wanzke, B. Winkeljann, A. M. Bergmann, O. Lieleg, J. Boekhoven
Regulating chemically fueled peptide assemblies by molecular design 
J. Am. Chem. Soc. (pdf)

46) C. Wanzke, M. Tena-Solsona, B. Rieß, and J. Boekhoven,
Emulsions of active droplets release drugs with a constant and tunable rate
Materials Horizons (pdf)

45) B. Rieß, R. Grötsch, J. Boekhoven,
The design of dissipative molecular assemblies driven by chemical reaction cycles,
Chem (pdf)

44)  C. Wanzke, A. Jussupow, F. Kohler, H. Dietz, V. R. I. Kaila, J. Boekhoven, 
Dynamic vesicles formed by dissipative self-assembly,
ChemSystemsChem (pdf)

2019

43) R. Grötsch, C. Wanzke, M. Speckbacher, Arzu Angi, B. Rieger, J. Boekhoven
Pathway dependence in the fuel-driven dissipative self-assembly of nanoparticles,
J. Am. Chem. Soc.  (pdf)

42) E. Edeleva, A. Salditt, J. Stamp, P. Schwintek, J. Boekhoven D. Braun
Continuous nonenzymatic cross-replication of DNA strands with in-situ activated short DNA oligonucleotides,
Chem. Sci.  (pdf)

41) M. Tena-Solsona, J. Boekhoven
Dissipative self-assembly of peptides,
Isr. J. Chem. (pdf)

40) J. Boekhoven,
Systems Chemistry: Out of Equilibrium,
ChemSystemsChem (pdf)

2018

39) J. Boekhoven
Complexity from small molecules,
Nature Nanotech. (pdf)

38) R. Grötsch*, A. Angı*, Y. G. Mideksa, C. Wanzke, M. Tena-Solsona, M. Feige, B. Rieger, J. Boekhoven
Dissipative Self-Assembly of Photoluminescent Silicon Nanocrystals,
Angew. Chem. Int. Ed. (pdf)
Dissipative Selbstassemblierung photolumineszierender Siliciumnanokristalle,
Angew. Chem. (pdf)

37) J. Boekhoven, D. Didier
Merging Art and Science—The 53rd Bürgenstock Conference,
Angew. Chem. Int. Ed. (pdf)
Vereinigung von Kunst und Wissenschaft: Die 53. Bürgenstock‐Konferenz
Angew. Chem.  (pdf)

36) B. Rieß, J. Boekhoven
Applications of dissipative supramolecular materials with a tunable lifetime
ChemNanoMat (pdf)

35) B. Rieß*, C. Wanzke*, M. Tena-Solsona, R. Grötsch , J. Boekhoven
Dissipative molecular assemblies that inhibit their own degradation
Soft Matter (pdf)

34) M. Tena-Solsona, B. Rieß, C. Wanzke, A. Bausch, J. Boekhoven
Self-selection of dissipative assemblies from primitive chemical reaction networks
Nature Commun. (pdf)
Press:
In the beginning was the phase separation, TUM News (link)
A simple mechanism could have been decisive for the development of life,  phys.org (link)
How Were the First Building Blocks of Life Stabilized? Chemistry Views (link)

31) C. Robidillo, M. Islam, M. Aghajamali, A. Faramus, R. Sinelnikov, X. Zhang, J. Boekhoven, J. Veinot
Functional Bioinorganic Hybrids from Enzymes and Luminescent Silicon-Based Nanoparticles
Langmuir (pdf)

32) B. Winkeljann, B. Käsdorf, J. Boekhoven, O.Lieleg
Macromolecular coating enables tunable selectivity in a porous PDMS matrix,
Macromol. Biosci. (pdf)

30) S. van Rossum,* M. Tena-Solsona,* J. van Esch, R. Eelkema, J. Boekhoven
Dissipative out-of-equilibrium assembly of man-made supramolecular material,
Chem. Soc. Rev. (pdf)

29) R. Freeman, N. Stephanopoulos, Z. Alvarez, J. Lewis , S. Sur, C. Serrano, J. Boekhoven, S. Lee, S. Stupp
Instructing Cells with Programmable Peptide DNA Hybrids,
Nature Commun. (pdf)
Press:
New technology to manipulate cells could one day help treat Parkinson’s, Northwestern News, (link)

28) R. Kazantsev, A. Dannenhoffer, A. Weingarten, B. Phelan, B. Harutyunyan, T.  Aytun, A.  Narayanan, D. Fairfield, J. Boekhoven, H. Sai, A. Senesi, P. O’Dogherty, L. Palmer, M. Bedzyk, M. Wasielewski, S. Stupp
Crystal Phase Transitions and Photocatalysis in Supramolecular Scaffolds,
J. Am. Chem. Soc. (pdf)

2016

27) T. Tantakitti,* J. Boekhoven*, X. Wang, R. Kazantsev, T. Yu, J. Li, E. Zhuang, R. Zandi, J. Ortony, C. Newcomb, L. Palmer, S. Gajendra, M. Olvera de la Cruz, G. Schatz, S. Stupp
Energy landscapes of supramolecular systems determine their function
Nature Materials, (pdf)

26) J. Boekhoven, A.  Brizard, M. Stuart, L. Florusse, G. Raffy, A. Del Guerzo, J. van Esch
Bio-inspired supramolecular materials by orthogonal self-assembly of hydrogelators and phospholipids
Chem. Sci. (pdf)

25) J. Poolman, C. Maity, J. Boekhoven, L. van der Mee, M. Groenewold, S. van Kasteren,  F. Versluis, J. van Esch, R. Eelkema
A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels
J. Mat. Chem B, (pdf)
Listed as J. Mat. Chem. B most accessed paper in 2016

24) E. Berns, Z. Álvarez, J. Goldberger, J. Boekhoven, J. Kessler, H. Kuhn, S. Stupp
A tenascin-C mimetic peptide amphiphile nanofiber gel promotes neurite outgrowth and cell migration of neurosphere-derived cells
Acta Biomaterialia, (pdf)

2015

23) J. Boekhoven,* W. Hendriksen,*  G.Koper, R. Eelkema, J. van Esch,
Transient assembly of active materials fueled by a chemical reaction
Science, (pdf)
Press:
S. Van der Zwaag, B. Meijer, Fueling connections between chemistry and biology Science (pdf)
M. Lavine, Nonequilibrium transient self-assembly  Science (pdf)

22) R. Freeman, J. Boekhoven, M. Dickerson, R. Naik, S. Stupp,
Biopolymers and Supramolecular Polymers As Biomaterials For Biomedical Applications
MRS Bulletins, (pdf)

21) J. Boekhoven, R. Zha, S. Stupp,
Alginate-peptide amphiphile core-shell microparticles as a targeted drug delivery system
RSC advances, (pdf)

2014

20) J. Boekhoven, S. Stupp,
Supramolecular Materials for Regenerative Medicine
Adv. Mater., (pdf)

19) C. Newcomb, S. Sur, J. Ortony, O. Lee, J. Matson, J. Boekhoven, J. Yu, G. Schatz, S. Stupp,
Cell death and cell survival instructed by supramolecular cohesion of biomaterials
Nature Commun., (pdf)

18) J. Poolman, J. Boekhoven, A. Besselink, A. Olive, J. van Esch, R. Eelkema,
Tuning gelation time and stiffness of low molecular weight hydrogels through catalytic control over self-assembly
Nature Protoc., (pdf)

17) R. Zha, S. Sur, J. Boekhoven, M. Zhang, S. Stupp
Supramolecular Assembly of Multifunctional Maspin-Mimetic Nanostructures as a Highly Potent Inhibitor of Angiogenesis
Acta. Biomateriala, (pdf)

16) S. Khan, S. Sur, P. Dankers, R. da Silva, J. Boekhoven, T. Poor, S. Stupp
Post-Assembly Functionalization of Supramolecular Nanostructures with Bioactive Peptides and Fluorescent Proteins by Native Chemical Ligation
Bioconjugate Chem., (pdf)

2013

15) J. Boekhoven, J. Poolman, C. Maity, F. Li, L. van der Mee, C. Minkenberg, J. van Esch, R. Eelkema
Catalytic control over supramolecular gel formation, Nature Chem. (pdf)
Press: TUDelta

14) J. Boekhoven, C. Rubert, S. Sur, A. Worthy, S. Stupp
“Dynamic Display of Bioactivity through Host–Guest Chemistry”
Angew. Chem. Int. Ed., (pdf)

113 H. Kassam, T. Moyer, J. Boekhoven, T. Chew, S. Stupp, M. Kibbe
“Binding of an intravascular delivery vehicle for prevention of arterial restenosis is contingent on tertiary structure”
J. Am. Coll. Surg., (pdf)

12) D. Janeliunas, P. van Rijn, J. Boekhoven, R. Eelkema, J. van Esch
Aggregation-driven reversible formation of conjugated polymers in water
Angew. Chem. Int. Ed., (pdf)

11) G. Koper, J. Boekhoven, W. Hendriksen, J. van Esch, R. Eelkema
The Lost Work in Dissipative Self-Assembly
Int. J. Thermophys., (pdf)

2012

10) J. Boekhoven, M. Koot, T. Wezendonk, R. Eelkema, J. van Esch
A Self-Assembled Delivery Platform with Post-production Tunable Release Rate
J. Am. Chem. Soc., (pdf)
Press: Chemistry and Industry Magazine (link)

9) C. Minkenberg, B. Homan, J. Boekhoven, B. Norder, R. Eelkema, J. van Esch
Responsive Wormlike Micelles from Dynamic Covalent Surfactants
Langmuir, (pdf)

8) M. Wadekar, J. Boekhoven, W. Jager, G. Koper, S. Picken
Micellization Behavior of Aromatic Moiety Bearing Hybrid Fluorocarbon Surfactants
Langmuir, (pdf)

2011

7) J. Boekhoven, A. Brizard, P. van Rijn, M. Stuart, R. Eelkema, J. van Esch
Programmed Morphological Transitions of Multisegment Assemblies by Molecular Chaperone Analogs
Angew. Chem. Int. Ed., (pdf)

6) C. Minkenberg, F. Li, P. van Rijn, L. Florusse, J. Boekhoven, G. Koper, R. Eelkema, J. van Esch
Responsive Vesicles from Dynamic Covalent Surfactants
Angew. Chem. Int. Ed., (pdf)
This work was highlighted in Nature (pdf)

2010

5) A. Hirst, S. Roy, M. Arora, A. Das, N. Hodson, P. Murray, P. Marshall, S. Javide, J. Sefcike, J. Boekhoven, J. van Esch, S. Santabarbara, N.Hunt, R. Ulijn
Biocatalytic Induction of Supramolecular Order, Nature Chem. (pdf)

4) J. Boekhoven, A. Brizard, K. Kowlgi, G. Koper, R. Eelkema, J. van Esch,
Dissipative Self-Assembly of a Molecular Gelator by Using a Chemical Fuel
Angew. Chem. Int. Ed. (pdf)
This work was nominated as a “Hot Paper” and was highlighted in Nature Chem (pdf)

3) J. Boekhoven, P van Rijn, A. Brizard, M. Stuart, J. van Esch
Size control and compartmentalisation in self-assembled nano-structures of a multisegment amphiphile, Chem. Commun. (pdf)

Book Chapters

2) R. Grötsch, J. Boekhoven
“Unique properties of supramolecular biomaterials through non-equilibrium self-assembly”, Chapter in: Self-assembled Biomaterials

1) J. Boekhoven, P. van Rijn, J. van Esch
“Self-Assembly of Facial Amphiphiles” Chapter in: Supramolecular Chemistry: From Molecules to Nanomaterials.

Theses

(10) 2019-2023 Dr. Alexander Bergmann
Dissipative Structures and Oscillations in Active Emulsions (pdf)

(9) 2019-2023 Dr. Laura Tebcharani
Zero-order drug delivery systems (pdf)

(8) 2019-2023 Dr. Michaela Würbser
Chemically fueled self-assembly approach toward life-like materials (pdf)

(7) 2018-2022 Dr. Carsten Donau
The Chemistry and Physics of Chemically Fueled Complex Coacervate Droplets (pdf)

(6) 2017-2022 Dr. Fabian Schnitter
Creating molecular memory through a carbodiimide-driven reaction cycle (pdf)

(5) 2017 – 2022 Dr. Patrick Schwarz
Designing Feedback Mechanisms in Chemically Fueled Emulsions (pdf)

(4) 2017-2021 Dr. Kun Dai
Design rules for the chemically fueled self-assembly and disassembly of peptides (pdf)

(3) 2016-2020 Dr. Caren Wanzke 
Development of Dissipative Supramolecular Materials – From Concept to Application (pdf)

(2) 2016 – 2020 Dr. Benedikt Rieß 
Development of Dissipative Out-of-Equilibrium Materials from Direct Chemical Reaction Cycles (pdf)

(1) 2016 – 2019 Dr. Raphael Grötsch 
Designing and Controlling Dissipative Self-Assembly of Nanoparticles (pdf)